Antimicrobial discovery from natural and unusual sources

Antimicrobial compounds from natural sources

Infectious diseases are one of the main causes of morbidity and mortality worldwide. Nowadays many infections are often caused by multi-resistant microorganisms resulting in difficult to treat diseases and, consequently, substantial increases in healthcare costs. The relative easy access to the antimicrobials and also the massive employment of these compounds for industrial purposes, including ...

Developing antimicrobial compounds from natural sources

Unconventional natural sources for future drug discovery.

Natural products used as food or drinks, clues from the fascinating science of zoopharmacognosy, terrestrial animals and their excreta, and many other NPs not primarily known for their medical use, seem to have, to a great extent, escaped the attention of natural product research. It is nevertheless highly probable that these sources could contain biologically active compounds, some of which wi...

anti-malarial discovery from plant sources: chemo-informatics approach

New concepts, experimental approaches, and dereplication strategies for the discovery of novel phytoestrogens from natural sources.

Phytoestrogens constitute an attractive research topic due to their estrogenic profile and their biological involvement in woman's health. Therefore, numerous studies are currently performed in natural products chemistry area aiming at the discovery of novel phytoestrogens. The main classes of phytoestrogens are flavonoids (flavonols, flavanones), isoflavonoids (isoflavones, coumestans), lignan...